听力与言语-语言病理学

行为科学

医学伦理学

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  • Relationship between brain and cognitive processes in Down syndrome.

    abstract::We investigated regional grey matter (GM) density in adolescents with Down syndrome (DS) compared to age-matched controls and correlated MRI data with neuropsychological measures in the DS group. Inter-group comparisons documented several GM concentration abnormalities in the participants with DS compared to controls....

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-011-9448-3

    authors: Menghini D,Costanzo F,Vicari S

    更新日期:2011-05-01 00:00:00

  • Genotype on the pigmentation regulating PMEL17 gene affects behavior in chickens raised without physical contact with conspecifics.

    abstract::Chickens homozygous for the Dominant white or wild-type allele of PMEL17 were subjected to a broad phenotyping in order to detect consistent differences between genotypes. To exclude feather pecking, the chickens were individually housed without physical contact, from the day of hatching, and tested for social, aggres...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9379-4

    authors: Karlsson AC,Mormede P,Kerje S,Jensen P

    更新日期:2011-03-01 00:00:00

  • Genetic regulation of pre-pubertal development of body mass index: a longitudinal study of Japanese twin boys and girls.

    abstract::We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the ma...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9380-y

    authors: Silventoinen K,Kaprio J,Yokoyama Y

    更新日期:2011-03-01 00:00:00

  • No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: the TRAILS study.

    abstract::Previously, sequence variation in the glucocorticoid (GR) and mineralocorticoid (MR) receptor genes (NR3C1 and NR3C2, respectively) have been found to be associated with physiological stress responses to social stress tests in small samples of adult men and oral contraceptives (OC) using women. Associations between si...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9385-6

    authors: Bouma EM,Riese H,Nolte IM,Oosterom E,Verhulst FC,Ormel J,Oldehinkel AJ

    更新日期:2011-03-01 00:00:00

  • Congenic mouse strains enable discrimination of genetic determinants contributing to fear and fear memory.

    abstract::The ability to learn and remember is variable within a population of a given species, including humans. This is due in part to genetic variation between individuals. However, only few genes have been identified that contribute to variation in learning and memory. Two inbred mouse strains, C57Bl/6J (B6) and DBA/2J (D2)...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9387-4

    authors: Wilson YM,Brodnicki TC,Lawrence AJ,Murphy M

    更新日期:2011-03-01 00:00:00

  • Genetic variance in a component of the language acquisition device: ROBO1 polymorphisms associated with phonological buffer deficits.

    abstract::The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9402-9

    authors: Bates TC,Luciano M,Medland SE,Montgomery GW,Wright MJ,Martin NG

    更新日期:2011-01-01 00:00:00

  • In search of the perfect phenotype: an analysis of linkage and association studies of reading and reading-related processes.

    abstract::Reading ability and specific reading disability (SRD) are complex traits involving several cognitive processes and are shaped by a complex interplay of genetic and environmental forces. Linkage studies of these traits have identified several susceptibility loci. Association studies have gone further in detecting candi...

    journal_title:Behavior genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10519-011-9444-7

    authors: Skiba T,Landi N,Wagner R,Grigorenko EL

    更新日期:2011-01-01 00:00:00

  • Family matters: happiness in nuclear families and twins.

    abstract::Biometric studies have shown that happiness is strongly affected by genes. The findings are mainly based on twin data, however, and the full validity of the results has been debated. To overcome some limitations in classical twin research, we examined aetiological sources of subjective well-being (SWB), using two inde...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9365-x

    authors: Nes RB,Czajkowski N,Tambs K

    更新日期:2010-09-01 00:00:00

  • Behavioral traits are affected by selective breeding for increased wheel-running behavior in mice.

    abstract::Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and "information gathering" in the open-field test, either wi...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9359-8

    authors: Jónás I,Schubert KA,Reijne AC,Scholte J,Garland T Jr,Gerkema MP,Scheurink AJ,Nyakas C,van Dijk G

    更新日期:2010-07-01 00:00:00

  • Wait for it! A twin study of inhibitory control in early childhood.

    abstract::Inhibitory control (IC) is a dimension of child temperament that emerges in toddlerhood and involves the ability to regulate behavior in response to instructions or expectations. In general, children with low levels of IC have more cognitive and social difficulties, and higher levels of problem behaviors. Unfortunatel...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9316-6

    authors: Gagne JR,Saudino KJ

    更新日期:2010-05-01 00:00:00

  • Estimating effect sizes in genome-wide association studies.

    abstract::Knowledge about the proportion of markers without effects (p( 0 )) and the effect sizes in large scale genetic studies is important to understand the basic properties of the data and for applications such as the control of false discoveries and designing adequately powered replication studies. Many p(0) estimators hav...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9321-9

    authors: Bukszár J,van den Oord EJ

    更新日期:2010-05-01 00:00:00

  • A twin study of intracerebral volumetric relationships.

    abstract::Using high resolution magnetic resonance imaging data, we examined the interrelationships between eight cerebral lobar volumetric measures via both exploratory and confirmatory factor analyses in a large sample (N = 484) of pediatric twins and singletons. These analyses suggest the presence of strong genetic correlati...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-010-9332-6

    authors: Schmitt JE,Wallace GL,Lenroot RK,Ordaz SE,Greenstein D,Clasen L,Kendler KS,Neale MC,Giedd JN

    更新日期:2010-03-01 00:00:00

  • A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples.

    abstract::Two separate genome-wide association studies were conducted to identify single nucleotide polymorphisms (SNPs) associated with social and nonsocial autistic-like traits. We predicted that we would find SNPs associated with social and non-social autistic-like traits and that different SNPs would be associated with soci...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9308-6

    authors: Ronald A,Butcher LM,Docherty S,Davis OS,Schalkwyk LC,Craig IW,Plomin R

    更新日期:2010-01-01 00:00:00

  • Feminization and alteration of Drosophila taste neurons induce reciprocal effects on male avoidance behavior.

    abstract::Taste perception allows most animals to find edible food, potential mates, and avoid ingesting toxic molecules. Intriguingly, a small group of Drosophila taste neurones (expressing Gr66a-Gal4) involved in the perception of bitter substances is also used to detect 7-tricosene (7-T), a male cuticular pheromone. Male fli...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9286-8

    authors: Lacaille F,Everaerts C,Ferveur JF

    更新日期:2009-09-01 00:00:00

  • Generalist genes and high cognitive abilities.

    abstract::The concept of generalist genes operating across diverse domains of cognitive abilities is now widely accepted. Much less is known about the etiology of the high extreme of performance. Is there more specialization at the high extreme? Using a representative sample of 4,000 12-year-old twin pairs from the UK Twins Ear...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9271-2

    authors: Haworth CM,Dale PS,Plomin R

    更新日期:2009-07-01 00:00:00

  • Bayesian composite model space approach for mapping quantitative trait Loci in variance component model.

    abstract::In this article, we successfully apply the novel model selection method, Bayesian composite model space approach which has been used to map quantitative trait loci (QTL) for allelic substitution model, to map QTL for variance component model. The novel model selection approach has two advantages compared to the revers...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-009-9259-y

    authors: Fang M,Liu S,Jiang D

    更新日期:2009-05-01 00:00:00

  • Genetic and environmental mediation between measures of personality and family environment in twins reared together.

    abstract::In this study we analyzed the etiology of the relationship between personality traits and retrospectively recalled family environment. The data of 226 identical and 168 fraternal twin pairs reared together from the Jena twin study of social attitudes were available. Personality traits were measured using the self- and...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-008-9238-8

    authors: Kandler C,Riemann R,Kämpfe N

    更新日期:2009-01-01 00:00:00

  • Natural genetic variation in complex mating behaviors of male Drosophila melanogaster.

    abstract::Mating behavior, including courtship and copulation, is a main component of male fitness, especially in species with no parental care. Variation in this behavior can thus be a target for mate choice and sexual selection, and can lead to evolution. The fruit fly, Drosophila melanogaster, has well-documented complex mal...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-008-9204-5

    authors: Ruedi EA,Hughes KA

    更新日期:2008-07-01 00:00:00

  • Do schools moderate the genetic determinants of smoking?

    abstract::This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our analysis relies on a sub-sample of 1,198 sibling and twin pairs nested within 84 schools. We develop a multile...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-008-9197-0

    authors: Boardman JD,Saint Onge JM,Haberstick BC,Timberlake DS,Hewitt JK

    更新日期:2008-05-01 00:00:00

  • Twin analysis on paired comparison data.

    abstract::Current behavior genetic models can only employ limited types of phenotypic data, such as Likert scale data or continuous data, as variables. Here, a new method employing paired comparison data is presented within the framework of behavior genetic models. This model facilitates the estimation of genetic, shared enviro...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-007-9183-y

    authors: Ozaki K

    更新日期:2008-03-01 00:00:00

  • Modeling genetic and environmental factors to increase heritability and ease the identification of candidate genes for birth weight: a twin study.

    abstract::Heritability estimates of birth weight have been inconsistent. Possible explanations are heritability changes during gestational age or the influence of covariates (e.g. chorionicity). The aim of this study was to model birth weights of twins across gestational age and to quantify the genetic and environmental compone...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-007-9170-3

    authors: Gielen M,Lindsey PJ,Derom C,Smeets HJ,Souren NY,Paulussen AD,Derom R,Nijhuis JG

    更新日期:2008-01-01 00:00:00

  • The G619A Aa-nat gene polymorphism does not contribute to sleep time variation in the Brazilian population.

    abstract::Genes involved in melatonin synthesis, such as Aa-nat, may be important for our understanding of diurnal preference and circadian rhythm disturbances in humans. In Japan, Hohjoh et al. reported increased allelic frequencies of the 619A allele of the G619A Aa-nat gene polymorphism in a sample of Delayed Sleep Phase Syn...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-007-9155-2

    authors: Pereira DS,Pedrazzoli M,Koike Bdel V,Louzada FM,Benedito-Silva AA,Lopez AR,Tufik S

    更新日期:2007-07-01 00:00:00

  • Genetic mixed linear models for twin survival data.

    abstract::Twin studies are useful for assessing the relative importance of genetic or heritable component from the environmental component. In this paper we develop a methodology to study the heritability of age-at-onset or lifespan traits, with application to analysis of twin survival data. Due to limited period of observation...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-007-9150-7

    authors: Ha ID,Lee Y,Pawitan Y

    更新日期:2007-07-01 00:00:00

  • Genetics and diagnostic refinement.

    abstract::For many psychiatric conditions it is speculated that, rather than being single disease entities, they are a set of several disorders sharing clinical features but having (partly) different underlying causes. The possibility of measuring genetic variation on a large scale has given researchers new hope of identifying ...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9135-y

    authors: van den Oord E,McClay J,York T,Murrelle L,Robles J

    更新日期:2007-05-01 00:00:00

  • Computation of individual latent variable scores from data with multiple missingness patterns.

    abstract::Latent variable models are used in biological and social sciences to investigate characteristics that are not directly measurable. The generation of individual scores of latent variables can simplify subsequent analyses. However, missing measurements in real data complicate the calculation of scores. Missing observati...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9123-2

    authors: Campbell DD,Rijsdijk FV,Sham PC

    更新日期:2007-03-01 00:00:00

  • Marriage and genetic variation across the lifespan: not a steady relationship?

    abstract::The prevalence of marriage varies across the lifespan, as does its importance to reproduction and the nurturance of children. We examined genetic and environmental influences on self-reported marriage at each decade from 20 through 70 years of age, using data collected for the Duke Dementia Study, a followed-up subset...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9132-1

    authors: Trumbetta SL,Markowitz EM,Gottesman II

    更新日期:2007-03-01 00:00:00

  • Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice.

    abstract::The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9122-3

    authors: Mozhui K,Hamre KM,Holmes A,Lu L,Williams RW

    更新日期:2007-01-01 00:00:00

  • Genetic analyses of maternal and teacher ratings on attention problems in 7-year-old Dutch twins.

    abstract::The goal of the present study is to examine genetic and environmental influences on maternal and teacher ratings of Attention Problems (AP) in 7-year-old children. Teachers completed the Teacher Report Form (N=2259 pairs), and mothers the Child Behavior Checklist (N=2057 pairs). Higher correlations were found in twins...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9084-5

    authors: Derks EM,Hudziak JJ,Van Beijsterveldt CE,Dolan CV,Boomsma DI

    更新日期:2006-11-01 00:00:00

  • Frequentist model-averaged estimators and tests for univariate twin models.

    abstract::Parameter estimates from analyses of univariate twin data usually do not reflect the uncertainty due to the model selection phase of the data analysis. To address the effect of model selection uncertainty on parameter estimates, we introduce frequentist model-averaged estimators for univariate twin data analysis that ...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-006-9065-8

    authors: Williams CJ,Christian JC

    更新日期:2006-09-01 00:00:00

  • Individual differences in puberty onset in girls: Bayesian estimation of heritabilities and genetic correlations.

    abstract::: We report heritabilities for individual differences in female pubertal development at the age of 12. Tanner data on breast and pubic hair development in girls and data on menarche were obtained from a total of 184 pairs of monozygotic and dizygotic twins. Genetic correlations were estimated to determine to what exte...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-9022-y

    authors: van den Berg SM,Setiawan A,Bartels M,Polderman TJ,van der Vaart AW,Boomsma DI

    更新日期:2006-03-01 00:00:00

  • The Inositol 1,4,5-triphosphate kinase1 gene affects olfactory reception in Drosophila melanogaster.

    abstract::The Inositol 1,4,5-triphosphate (IP3) route is one of the two main transduction cascades that mediate olfactory reception in Drosophila melanogaster. The activity of IP3 kinase1 reduces the levels of this substrate by phosphorylation into inositol 1,3,4,5-tetrakiphosphate (IP4). We show here that the gene is expressed...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-9031-x

    authors: Gomez-Diaz C,Martin F,Alcorta E

    更新日期:2006-03-01 00:00:00

  • Genome-wide scan of IQ finds significant linkage to a quantitative trait locus on 2q.

    abstract::A genome-wide linkage scan of 795 microsatellite markers (761 autosomal, 34 X chromosome) was performed on Multidimensional Aptitude Battery subtests and verbal, performance and full scale scores, the WAIS-R Digit Symbol subtest, and two word-recognition tests (Schonell Graded Word Reading Test, Cambridge Contextual R...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-9003-1

    authors: Luciano M,Wright MJ,Duffy DL,Wainwright MA,Zhu G,Evans DM,Geffen GM,Montgomery GW,Martin NG

    更新日期:2006-01-01 00:00:00

  • Combined linkage and association analyses of the 124-bp allele of marker D2S2944 with anxiety, depression, neuroticism and major depression.

    abstract::A central issue in psychiatric genetics is whether positive findings replicate. Zubenko et al. (2002b, Mol. Psychiatry 7:460-467) reported an association of the 124-bp allele of D2S2944 with recurrent early-onset major depression for females. We tested for association of this allele to continuous measures of anxiety, ...

    journal_title:Behavior genetics

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10519-005-9006-y

    authors: Beem AL,Geus EJ,Hottenga JJ,Sullivan PF,Willemsen G,Slagboom PE,Boomsma DI

    更新日期:2006-01-01 00:00:00

  • Assortative mating in Drosophila adapted to a microsite ecological gradient.

    abstract::Elucidating the causes of population divergence, and ultimately speciation, is a central objective of evolutionary biology. A number of previous studies of Drosophila populations from the Nahal Oren canyon (Mt Carmel, Israel) revealed significant interslope differences for a complex of fitness and behavioral traits. P...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-6119-2

    authors: Singh SR,Rashkovetsky E,Iliadi K,Nevo E,Korol A

    更新日期:2005-11-01 00:00:00

  • Mixed-effects variance components models for biometric family analyses.

    abstract::Recent substantive research on biometric analyses of twin and family data has used both a biometric path analysis model (PAM) and a biometric variance components model (VCM). Methodological research on these same topics have suggested benefits of using linear structural equation model algorithms (SEMA) as well as mixe...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-2868-1

    authors: McArdle JJ,Prescott CA

    更新日期:2005-09-01 00:00:00

  • Contributions of genes and environments to stability and change in externalizing and internalizing problems during elementary and middle school.

    abstract::We examined longitudinally collected behavioral reports by teachers on a unique twin sample at the ages of 7, 8, 9, 10, 11, and 12 years. As twin and adoption studies implicate the role of genetic influence on behavioral problems found to be stable in epidemiological samples, the current study employs a developmental ...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-004-1747-5

    authors: Haberstick BC,Schmitz S,Young SE,Hewitt JK

    更新日期:2005-07-01 00:00:00

  • Mx scripts library: structural equation modeling scripts for twin and family data.

    abstract::Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/or longitudinal data, incorp...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-2791-5

    authors: Posthuma D,Boomsma DI

    更新日期:2005-07-01 00:00:00

  • Experimental manipulation of sexual selection and the evolution of courtship song in Drosophila pseudoobscura.

    abstract::Courtship song serves as a sexual signal and may contribute to reproductive isolation between closely related species. Using lines of Drosophila pseudoobscura experimentally selected under different sexual selection regimes, we tested whether increased promiscuity and enforced monogamy led to evolutionary changes in c...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-005-3217-0

    authors: Snook RR,Robertson A,Crudgington HS,Ritchie MG

    更新日期:2005-05-01 00:00:00

  • Handedness in children of schizophrenic parents: data from three high-risk studies.

    abstract::This is the first report of data analyses from a consortium of longitudinal genetic-risk studies on offspring of schizophrenic parents (CLOSSER) who were followed from birth or mid-childhood to their early 20's or considerably older ages. Three of the CLOSSER studies provide data to enable us to address long-persistin...

    journal_title:Behavior genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10519-005-3227-y

    authors: Erlenmeyer-Kimling L,Hans S,Ingraham L,Marcus J,Wynne L,Rehman A,Roberts SA,Auerbach J

    更新日期:2005-05-01 00:00:00

  • Multivariate genetic analysis of chronic pelvic pain and associated phenotypes.

    abstract::Chronic pelvic pain (CPP) is a common condition in women that is difficult to diagnose. Although heritability estimates have been published for some conditions potentially underlying pelvic pain, the heritability of CPP itself has never been investigated. Using data from 623 MZ and 377 DZ female twin pairs aged 29-50 ...

    journal_title:Behavior genetics

    pub_type: 杂志文章

    doi:10.1007/s10519-004-1017-6

    authors: Zondervan KT,Cardon LR,Kennedy SH,Martin NG,Treloar SA

    更新日期:2005-03-01 00:00:00

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